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The Dangers of Mixing Alcohol and Drugs

Woman holding a glass of wine in one hand and a pill in the other - dangers of mixing alcohol and drugs

Mixing alcohol and drugs is a dangerous combination that can have serious, even life-threatening, consequences. Alcohol slows down your brain and body, affecting your coordination, judgment, and reaction time. When you add drugs into the mix, the effects can become even more unpredictable—and far more dangerous. The risk is especially high with opioids or sedatives, which can slow your breathing to a dangerously low level, sometimes to the point of stopping altogether. What might seem like a harmless decision at the moment can quickly turn into a medical emergency.

The Dangers of Mixing Alcohol with Illicit Drugs

Mixing alcohol with illicit drugs can be extremely dangerous, leading to severe health risks and unpredictable outcomes. The interaction effects vary depending on the type of drug involved.

  • Stimulants, such as cocaine and methamphetamine: Mixing alcohol with stimulants can mask the effects of alcohol, leading individuals to consume more than they normally would. This can result in increased heart rate, high blood pressure, and an increased risk of heart attack or stroke. The combination can also lead to risky behaviors due to impaired judgment.
  • Depressants, such as heroin and benzodiazepines: Alcohol and depressants both slow down the central nervous system. When combined, they can enhance each other’s effects, leading to extreme drowsiness, difficulty breathing, and even overdose. This combination is particularly hazardous because it can suppress vital functions.
  • Hallucinogens, such as LSD and psilocybin: The effects of alcohol mixed with hallucinogens can be unpredictable. Alcohol might dull the mind-altering effects of hallucinogens or, in some cases, intensify the confusion and disorientation they cause. This can result in anxiety, panic, or risky behaviors.
  • Cannabis: While not considered an illicit drug in many places, mixing cannabis with alcohol can still be dangerous. Alcohol can increase the absorption of THC, the active component in cannabis, leading to heightened impairment. This combination can result in nausea, dizziness, anxiety, and increased impairment.

The Dangers of Mixing Alcohol with Prescription Medications

Mixing alcohol with prescription medications can be highly risky and may lead to serious health issues. Alcohol may also interfere with how the body absorbs and processes medications, which can either decrease their effectiveness or increase the concentration in the bloodstream, leading to toxicity. This is particularly concerning with painkillers, antidepressants, or sedatives, where interactions can lead to life-threatening situations. 

Here is a list of common medications and the possible effects of consuming them with alcohol:

  • Antidepressants: Combining alcohol with antidepressants like SSRIs or MAOIs can increase symptoms of depression and anxiety. It may also lead to drowsiness, dizziness, and impaired motor skills, raising the risk of accidents.
  • Benzodiazepines: Medications such as Xanax and Valium, when mixed with alcohol, can cause severe drowsiness, slowed breathing, and even life-threatening respiratory depression. Medscape explains that this combination greatly increases the risk of motor vehicle crashes.
  • Opioids: Mixing alcohol with opioid painkillers like oxycodone or hydrocodone can greatly enhance the sedative effects, which can lead to extreme drowsiness, slowed breathing, overdose, and potentially fatal outcomes.
  • Antihistamines: Combining alcohol with antihistamines can lead to increased drowsiness and dizziness, impacting coordination and reaction times.
  • Antibiotics: Some antibiotics, such as metronidazole or tinidazole, can cause severe nausea, vomiting, and flushing when taken with alcohol. This interaction can also reduce the effectiveness of the antibiotic.
  • Blood Thinners: Alcohol can enhance the blood-thinning effects of medications like warfarin, increasing the risk of bleeding and bruising.
  • Diabetes Medications: Drinking alcohol while on insulin or oral diabetes medications can lead to dangerously low blood sugar levels, causing dizziness, confusion, and fainting.
  • Antipsychotics: Alcohol can amplify the sedative effects of antipsychotic medications, resulting in heightened drowsiness, dizziness, and increased risk of accidents.

The Dangers of Mixing Alcohol with Over-the-Counter (OTC) Medications

Mixing alcohol with over-the-counter (OTC) medications can be risky and may lead to harmful health effects. Alcohol can interact with these medications in ways that enhance side effects, reduce effectiveness, or cause unpredictable reactions. Below are the types of common OTC medications and their potential effects when combined with alcohol:

  • Pain relievers, such as acetaminophen and ibuprofen: Combining acetaminophen with alcohol can increase the risk of liver damage. Alcohol can also enhance the stomach-irritating effects of ibuprofen, potentially leading to stomach ulcers or bleeding.
  • Cold and allergy medications such as antihistamines: Both alcohol and antihistamines can cause drowsiness. When taken together, this sedative effect can be intensified, impairing coordination and concentration, and increasing the risk of accidents.
  • Cough syrups, often containing dextromethorphan: Mixing these can lead to increased dizziness, drowsiness, and difficulty concentrating. Some individuals may also experience impaired judgment.
  • Sleep aids containing diphenhydramine, such as Benadryl: Alcohol can enhance the sedative effects of sleep aids, leading to severe drowsiness and increased risk of overdose.
  • Digestive aids, such as antacids and anti-diarrheal medications: While these generally have fewer interactions, alcohol can affect how well they work or exacerbate certain conditions like acid reflux.
  • Dietary supplements and herbal remedies, such as St. John’s Wort and ginseng: Alcohol can alter the effectiveness of these supplements or cause unexpected reactions, such as increased drowsiness or elevated blood pressure.

Do You Need Help?

If you or someone you care about is struggling with substance addiction, the caring professionals at Canyon Vista Recovery Center in Mesa, Arizona, can help. Our professional team will provide the resources and skills to regain control of your life. Reach out to us today.

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